Alignment of synaptic vesicle macromolecules with the macromolecules in active zone material that direct vesicle docking.

Synaptic vesicles dock at active zones on the presynaptic plasma membrane of a neuron's axon terminals as a precondition for fusing with the membrane and releasing their neurotransmitter to mediate synaptic impulse transmission. Typically, docked vesicles are next to aggregates of plasma membra...

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Bibliographic Details
Main Authors: Mark L Harlow, Joseph A Szule, Jing Xu, Jae Hoon Jung, Robert M Marshall, Uel J McMahan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3718691?pdf=render