GPS-ARM: computational analysis of the APC/C recognition motif by predicting D-boxes and KEN-boxes.

Anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase incorporated with Cdh1 and/or Cdc20 recognizes and interacts with specific substrates, and faithfully orchestrates the proper cell cycle events by targeting proteins for proteasomal degradation. Experimental identification of APC/C...

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Bibliographic Details
Main Authors: Zexian Liu, Fang Yuan, Jian Ren, Jun Cao, Yanhong Zhou, Qing Yang, Yu Xue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3315528?pdf=render