Theory of Structural and Secondary Relaxation in Amorphous Drugs under Compression

Compression effects on alpha and beta relaxation process of amorphous drugs are theoretically investigated by developing the elastically collective nonlinear Langevin equation theory. We describe the structural relaxation as a coupling between local and nonlocal activated process. Meanwhile, the sec...

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Bibliographic Details
Main Authors: Anh D. Phan, Katsunori Wakabayashi
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/2/177