Lack of mutations of exon 2 of the MEN1 gene in endocrine and nonendocrine sporadic tumors

Lack of mutations of exon 2 of the MEN1 gene in endocrine and nonendocrine sporadic tumors

In addition to the mutations that underlie most cases of the multiple endocrine neoplasia type 1 (MEN1) syndrome, somatic mutations of the MEN1 gene have also been described in sporadic tumors like gastrinomas, insulinomas and bronchial carcinoid neoplasm. We examined exon 2 of this gene, where most...

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Bibliographic Details
Main Authors: S.C. Costa, L.S. Nascimento, F.J. Ferreira, P.S. Mattos, L.H. Camara-Lopes, L.S. Ward
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
MEN1 gene
sporadic tumors
thyroid
adrenal
breast
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000700004

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000700004

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