Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages

Myeloperoxidase (MPO) is a vital component of the innate immune system, which produces the potent oxidant hypochlorous acid (HOCl) to kill invading pathogens. However, an overproduction of HOCl during chronic inflammatory conditions causes damage to host cells, which promotes disease, including athe...

Full description

Bibliographic Details
Main Authors: Chaorui Guo, Michael J. Davies, Clare L. Hawkins
Format: Article
Published: Elsevier 2020-09-01
Series:Redox Biology
Online Access: