Combination of cytokine responses indicative of latent TB and active TB in Malawian adults.

An IFN-γ response to M. tuberculosis-specific antigens is an effective biomarker for M. tuberculosis infection but it cannot discriminate between latent TB infection and active TB disease. Combining a number of cytokine/chemokine responses to M. tuberculosis antigens may enable differentiation of la...

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Bibliographic Details
Main Authors: Yun-Gyoung Hur, Patricia Gorak-Stolinska, Anne Ben-Smith, Maeve K Lalor, Steven Chaguluka, Russell Dacombe, T Mark Doherty, Tom H Ottenhoff, Hazel M Dockrell, Amelia C Crampin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3832606?pdf=render