Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour

The role of chemoreceptors on vomeronasal neurons are not fully understood. Here the authors show that in mice, the vomeronasal chemoreceptor Fpr3 responds to peptides from the bacterial MgrB protein, and that exposure to these peptides drives an avoidance response.

Bibliographic Details
Main Authors: Bernd Bufe, Yannick Teuchert, Andreas Schmid, Martina Pyrski, Anabel Pérez-Gómez, Janina Eisenbeis, Thomas Timm, Tomohiro Ishii, Günter Lochnit, Markus Bischoff, Peter Mombaerts, Trese Leinders-Zufall, Frank Zufall
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12842-x