Liposome Consolidated with Cyclodextrin Provides Prolonged Drug Retention Resulting in Increased Drug Bioavailability in Brain
Although butylidenephthalide (BP) is an efficient anticancer drug, its poor bioavailability renders it ineffective for treating drug-resistant brain tumors. However, this problem is overcome through the use of noninvasive delivery systems, including intranasal administration. Herein, the bioavailabi...
Main Authors: | En-Yi Lin, Yu-Shuan Chen, Yuan-Sheng Li, Syuan-Rong Chen, Chia-Hung Lee, Mao-Hsuan Huang, Hong-Meng Chuang, Horng-Jyh Harn, Hsueh-Hui Yang, Shinn-Zong Lin, Dar-Fu Tai, Tzyy-Wen Chiou |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/12/4408 |
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