Combination anti-PD1 and ipilimumab therapy in patients with advanced melanoma and pre-existing autoimmune disorders

Background Clinical trials of immunotherapy have excluded patients with pre-existing autoimmune disease. While the safety and efficacy of single agent ipilimumab and anti-PD1 antibodies in patients with autoimmune disease has been examined in retrospective studies, no data are available for combinat...

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Bibliographic Details
Main Authors: Andrew Haydon, Shahneen Sandhu, Georgina V Long, Prachi Bhave, Alison Weppler, Matteo S Carlino, Lauren J Brown, Clara Allayous, J. Randall Patrinely Jr, Alexander A Menzies
Format: Article
Language:English
Published: BMJ Publishing Group 2021-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/5/e002121.full