The conjugation of nonsteroidal anti-inflammatory drugs (NSAID) to small peptides for generating multifunctional supramolecular nanofibers/hydrogels

The conjugation of nonsteroidal anti-inflammatory drugs (NSAID) to small peptides for generating multifunctional supramolecular nanofibers/hydrogels

Here we report supramolecular hydrogelators made of nonsteroidal anti-inflammatory drugs (NSAID) and small peptides. The covalent linkage of Phe–Phe and NSAIDs results in conjugates that self-assemble in water to form molecular nanofibers as the matrices of hydrogels. When the NSAID is naproxen (1),...

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Bibliographic Details
Main Authors: Jiayang Li, Yi Kuang, Junfeng Shi, Yuan Gao, Jie Zhou, Bing Xu
Format: Article
Language:English
Published: Beilstein-Institut 2013-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
self-delivery
hydrogel
multifunctional
nanofibers
NSAID
self-assembly
supramolecular
topical use
Online Access:https://doi.org/10.3762/bjoc.9.104

Internet

https://doi.org/10.3762/bjoc.9.104

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