Changes in B Cell Pool of Patients With Multibacillary Leprosy: Diminished Memory B Cell and Enhanced Mature B in Peripheral Blood

Changes in B Cell Pool of Patients With Multibacillary Leprosy: Diminished Memory B Cell and Enhanced Mature B in Peripheral Blood

Despite being treatable, leprosy still represents a major public health problem, and many mechanisms that drive leprosy immunopathogenesis still need to be elucidated. B cells play important roles in immune defense, being classified in different subgroups that present distinct roles in the immune re...

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Bibliographic Details
Main Authors: Otto Castro Nogueira, Mariana Gandini, Natasha Cabral, Vilma de Figueiredo, Rodrigo Nunes Rodrigues-da-Silva, Josué da Costa Lima-Junior, Roberta Olmo Pinheiro, Geraldo Moura Batista Pereira, Maria Cristina Vidal Pessolani, Cristiana Santos de Macedo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Mycobacterium leprae
B lymphocytes
B cell differentiation
active immune response
erythema nodosum leprosum
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.727580/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.727580/full

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