The development of a specific and sensitive LC-MS-based method for the detection and quantification of hydroperoxy- and hydroxydocosahexaenoic acids as a tool for lipidomic analysis.

The development of a specific and sensitive LC-MS-based method for the detection and quantification of hydroperoxy- and hydroxydocosahexaenoic acids as a tool for lipidomic analysis.

Docosahexaenoic acid (DHA) is an n-3 polyunsaturated fatty acid that is highly enriched in the brain, and the oxidation products of DHA are present or increased during neurodegenerative disease progression. The characterization of the oxidation products of DHA is critical to understanding the roles...

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Bibliographic Details
Main Authors: Priscilla B M C Derogis, Florêncio P Freitas, Anna S F Marques, Daniela Cunha, Patricia P Appolinário, Fernando de Paula, Tiago C Lourenço, Michael Murgu, Paolo Di Mascio, Marisa H G Medeiros, Sayuri Miyamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3812029?pdf=render

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http://europepmc.org/articles/PMC3812029?pdf=render

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