S-Equol mitigates motivational deficits and dysregulation associated with HIV-1

Abstract Motivational deficits (e.g., apathy) and dysregulation (e.g., addiction) in HIV-1 seropositive individuals, despite treatment with combination antiretroviral therapy, necessitates the development of innovative adjunctive therapeutics. S-Equol (SE), a selective estrogen receptor β agonist, h...

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Bibliographic Details
Main Authors: Kristen A. McLaurin, Sarah J. Bertrand, Jessica M. Illenberger, Steven B. Harrod, Charles F. Mactutus, Rosemarie M. Booze
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91240-0