Integrated Transcriptome Profiling Revealed That Elevated Long Non-Coding RNA-AC007278.2 Expression Repressed CCR7 Transcription in Systemic Lupus Erythematosus

Integrated Transcriptome Profiling Revealed That Elevated Long Non-Coding RNA-AC007278.2 Expression Repressed CCR7 Transcription in Systemic Lupus Erythematosus

PurposeSystemic lupus erythematosus (SLE) is a serious autoimmune disease. Its molecular pathogenesis, especially the long non-coding RNA (lncRNA) function, remains unclear. We want to investigate the lncRNA dysregulation profile and their molecular mechanisms in SLE.MethodsIn this study, we analyze...

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Bibliographic Details
Main Authors: Yi You, Xingwang Zhao, Yaguang Wu, Jiangming Mao, Lan Ge, Junkai Guo, Chenglei Zhao, Dong Chen, Zhiqiang Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
SLE
PBMCs
RNA-seq
lncRNAs
CCR7
Tfh cell differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.615859/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.615859/full

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