Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex.

p300, a ubiquitous transcription coactivator, plays an important role in gene activation. Our previous work demonstrated that human inducible nitric oxide synthase (hiNOS) expression can be highly induced with the cytokine mixture (CM) of TNF-α + IL-1β + IFN-γ. In this study, we investigated the fun...

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Bibliographic Details
Main Authors: Zhong Guo, Liang Zheng, Xinghua Liao, David Geller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4713468?pdf=render