Purinergic regulation of vascular tone in the retrotrapezoid nucleus is specialized to support the drive to breathe

Purinergic regulation of vascular tone in the retrotrapezoid nucleus is specialized to support the drive to breathe

Cerebral blood flow is highly sensitive to changes in CO2/H+ where an increase in CO2/H+ causes vasodilation and increased blood flow. Tissue CO2/H+ also functions as the main stimulus for breathing by activating chemosensitive neurons that control respiratory output. Considering that CO2/H+-induced...

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Bibliographic Details
Main Authors: Virginia E Hawkins, Ana C Takakura, Ashley Trinh, Milene R Malheiros-Lima, Colin M Cleary, Ian C Wenker, Todd Dubreuil, Elliot M Rodriguez, Mark T Nelson, Thiago S Moreira, Daniel K Mulkey
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-04-01
Series:eLife
Subjects:
arteriole
breathing
chemoreception
ATP
Online Access:https://elifesciences.org/articles/25232

Internet

https://elifesciences.org/articles/25232

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