TRPM8 Channels: Advances in Structural Studies and Pharmacological Modulation

TRPM8 Channels: Advances in Structural Studies and Pharmacological Modulation

The transient receptor potential melastatin subtype 8 (TRPM8) is a cold sensor in humans, activated by low temperatures (>10, <28 °C), but also a polymodal ion channel, stimulated by voltage, pressure, cooling compounds (menthol, icilin), and hyperosmolarity. An increased number of experimenta...

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Bibliographic Details
Main Authors: Carolina Izquierdo, Mercedes Martín-Martínez, Isabel Gómez-Monterrey, Rosario González-Muñiz
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
TRPM8 channels
expression
structure
agonists
antagonists
clinical trials
Online Access:https://www.mdpi.com/1422-0067/22/16/8502

Internet

https://www.mdpi.com/1422-0067/22/16/8502

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