Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice

In Alzheimer’s disease (AD), several studies have reported blood-brain barrier (BBB) breakdown with compromised function. P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are transport proteins localized at the BBB luminal membrane and play an important role in the clearance of amyl...

Full description

Bibliographic Details
Main Authors: Ihab M. Abdallah, Kamal M. Al-Shami, Euitaek Yang, Amal Kaddoumi
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
CAA
Online Access:https://www.mdpi.com/1422-0067/22/3/1231