Selectively driving cholinergic fibers optically in the thalamic reticular nucleus promotes sleep

Selectively driving cholinergic fibers optically in the thalamic reticular nucleus promotes sleep

Cholinergic projections from the basal forebrain and brainstem are thought to play important roles in rapid eye movement (REM) sleep and arousal. Using transgenic mice in which channelrhdopsin-2 is selectively expressed in cholinergic neurons, we show that optical stimulation of cholinergic inputs t...

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Bibliographic Details
Main Authors: Kun-Ming Ni, Xiao-Jun Hou, Ci-Hang Yang, Ping Dong, Yue Li, Ying Zhang, Ping Jiang, Darwin K Berg, Shumin Duan, Xiao-Ming Li
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-02-01
Series:eLife
Subjects:
TRN
Cholinergic projections
Optogenetics
GABAergic neurons
Sleep
Online Access:https://elifesciences.org/articles/10382

Internet

https://elifesciences.org/articles/10382

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