The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition

<p>Abstract</p> <p>Background</p> <p>Aberrations in the Wnt pathway have been reported to be involved in the metastasis of prostate cancer (PCa) to bone. We investigated the effect and underlying mechanism of a naturally-occurring Wnt inhibitor, WIF1, on the growth and...

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Bibliographic Details
Main Authors: Xie Jun, Atreya Dash, McQueen Peter, Ghaffar Samia, Guo Yi, Liu Zhongbo, Li Xuesen, Tang Yaxiong, Yee David S, Simoneau Anne R, Hoang Bang H, Zi Xiaolin
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/162