The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition
<p>Abstract</p> <p>Background</p> <p>Aberrations in the Wnt pathway have been reported to be involved in the metastasis of prostate cancer (PCa) to bone. We investigated the effect and underlying mechanism of a naturally-occurring Wnt inhibitor, WIF1, on the growth and...
Main Authors: | Xie Jun, Atreya Dash, McQueen Peter, Ghaffar Samia, Guo Yi, Liu Zhongbo, Li Xuesen, Tang Yaxiong, Yee David S, Simoneau Anne R, Hoang Bang H, Zi Xiaolin |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-06-01
|
Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/162 |
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