Adenoviral vector type 26 encoding Zika virus (ZIKV) M-Env antigen induces humoral and cellular immune responses and protects mice and nonhuman primates against ZIKV challenge.

Adenoviral vector type 26 encoding Zika virus (ZIKV) M-Env antigen induces humoral and cellular immune responses and protects mice and nonhuman primates against ZIKV challenge.

In 2015, there was a large outbreak of Zika virus (ZIKV) in Brazil. Despite its relatively mild impact on healthy adults, ZIKV infection during pregnancy has been associated with severe birth defects. Currently, there is no ZIKV vaccine available, but several vaccine candidates based on the ZIKV mem...

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Bibliographic Details
Main Authors: Freek Cox, Leslie van der Fits, Peter Abbink, Rafael A Larocca, Ella van Huizen, Eirikur Saeland, Janneke Verhagen, Rebecca Peterson, Jeroen Tolboom, Baerbel Kaufmann, Hanneke Schuitemaker, Dan H Barouch, Roland Zahn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6108497?pdf=render

Internet

http://europepmc.org/articles/PMC6108497?pdf=render

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