Matrilin-2 Is Proteolytically Cleaved by ADAMTS-4 and ADAMTS-5

Matrilin-2 is a widely distributed, oligomeric extracellular matrix protein that forms a filamentous network by binding to a variety of different extracellular matrix proteins. We found matrilin-2 proteolytic products in transfected cell lines in vitro and in mouse tissues in vivo. Two putative cle...

Full description

Bibliographic Details
Main Authors: Zhengke Wang, Junming Luo, Satori Iwamoto, Qian Chen
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/6/8472