β-Lactam Antibiotics—Drug-Drug Interaction Mediated by Organic Anion Transporters OAT1 and OAT3

Organic anion transporters OAT1 and OAT3 play a key role in elimination of most β-lactam antibiotics. Since nonsteroidal anti-inflammatory drugs, antivirals, antitumor agents, and some other drugs are also substrates of OAT1/3, this enables drug-drug interaction (DDI). The aim of the study was to an...

Full description

Bibliographic Details
Main Authors: I. A. Mazerkina, V. A. Evteev, A. B. Prokofiev, O. V. Muslimova, E. Yu. Demchenkova
Format: Article
Language:Russian
Published: OOO “Vashe Tsifrovoe Izdatelstvo” 2020-09-01
Series:Ведомости Научного центра экспертизы средств медицинского применения
Subjects:
Online Access:https://www.vedomostincesmp.ru/jour/article/view/308