Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC1

Identification of germ cell-specific Mga variant mRNA that promotes meiosis via impediment of a non-canonical PRC1

Abstract A non-canonical PRC1 (PRC1.6) prevents precocious meiotic onset. Germ cells alleviate its negative effect by reducing their amount of MAX, a component of PRC1.6, as a prerequisite for their bona fide meiosis. Here, we found that germ cells produced Mga variant mRNA bearing a premature termi...

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Bibliographic Details
Main Authors: Yuka Kitamura, Kousuke Uranishi, Masataka Hirasaki, Masazumi Nishimoto, Ayumu Suzuki, Akihiko Okuda
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89123-5

Internet

https://doi.org/10.1038/s41598-021-89123-5

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