A joint modeling approach for longitudinal microbiome data improves ability to detect microbiome associations with disease.

Changes in the composition of the microbiome over time are associated with myriad human illnesses. Unfortunately, the lack of analytic techniques has hindered researchers' ability to quantify the association between longitudinal microbial composition and time-to-event outcomes. Prior methodolog...

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Bibliographic Details
Main Authors: Pamela N Luna, Jonathan M Mansbach, Chad A Shaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008473