Intragenic sequences in the trophectoderm harbour the greatest proportion of methylation errors in day 17 bovine conceptuses generated using assisted reproductive technologies

Intragenic sequences in the trophectoderm harbour the greatest proportion of methylation errors in day 17 bovine conceptuses generated using assisted reproductive technologies

Abstract Background Assisted reproductive technologies (ART) are widely used to treat fertility issues in humans and for the production of embryos in mammalian livestock. The use of these techniques, however, is not without consequence as they are often associated with inauspicious pre- and postnata...

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Bibliographic Details
Main Authors: Alan M. O’Doherty, Paul McGettigan, Rachelle E. Irwin, David A. Magee, Dominic Gagne, Eric Fournier, Abdullah Al-Naib, Marc-André Sirard, Colum P. Walsh, Claude Robert, Trudee Fair
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Genomics
Subjects:
Assisted reproduction technologies (ART)
Epigenetics
DNA methylation
Embryo
Gene body
Bovine
Online Access:http://link.springer.com/article/10.1186/s12864-018-4818-3

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http://link.springer.com/article/10.1186/s12864-018-4818-3

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