The Cancer SENESCopedia: A delineation of cancer cell senescence

The Cancer SENESCopedia: A delineation of cancer cell senescence

Summary: Cellular senescence is characterized as a stable proliferation arrest that can be triggered by multiple stresses. Most knowledge about senescent cells is obtained from studies in primary cells. However, senescence features may be different in cancer cells, since the pathways that are involv...

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Main Authors: Fleur Jochems, Bram Thijssen, Giulia De Conti, Robin Jansen, Ziva Pogacar, Kelvin Groot, Liqin Wang, Arnout Schepers, Cun Wang, Haojie Jin, Roderick L. Beijersbergen, Rodrigo Leite de Oliveira, Lodewyk F.A. Wessels, René Bernards
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
senescence
cancer
ABT-263
gene expression classifier
transcriptome profiling
senolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721008585

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http://www.sciencedirect.com/science/article/pii/S2211124721008585

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