Neuroprotective dobutamine treatment upregulates superoxide dismutase 3, anti-oxidant and survival genes and attenuates genes mediating inflammation

Neuroprotective dobutamine treatment upregulates superoxide dismutase 3, anti-oxidant and survival genes and attenuates genes mediating inflammation

Abstract Background Labor subjects the fetus to an hypoxic episode and concomitant adrenomodullary catecholamine surge that may provide protection against the hypoxic insult. The beta1-adrenergic agonist dobutamine protects against hypoxia/aglycemia induced neuronal damage. We aimed to identify the...

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Bibliographic Details
Main Authors: Tina Markus, David Ley, Stefan R. Hansson, Tadeusz Wieloch, Karsten Ruscher
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Neuroscience
Subjects:
Dobutamine
Gene array
Hippocampal slice cultures
Hypoxia
Lipopolysaccharide
Preconditioning
Online Access:http://link.springer.com/article/10.1186/s12868-018-0415-2

Internet

http://link.springer.com/article/10.1186/s12868-018-0415-2

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