Evaluation of antimalarial activity and toxicity of a new primaquine prodrug.

Evaluation of antimalarial activity and toxicity of a new primaquine prodrug.

Plasmodium vivax is the most prevalent of the five species causing malaria in humans. The current available treatment for P. vivax malaria is limited and unsatisfactory due to at least two drawbacks: the undesirable side effects of primaquine (PQ) and drug resistance to chloroquine. Phenylalanine-al...

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Bibliographic Details
Main Authors: Marcelo Gomes Davanço, Anna Caroline Campos Aguiar, Leandro Alves Dos Santos, Elias Carvalho Padilha, Michel Leandro Campos, Cleverton Roberto de Andrade, Luiz Marcos da Fonseca, Jean Leandro Dos Santos, Chung Man Chin, Antoniana Ursine Krettli, Rosangela Gonçalves Peccinini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136845?pdf=render

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http://europepmc.org/articles/PMC4136845?pdf=render

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