Gene and MicroRNA transcriptome analysis of Parkinson's related LRRK2 mouse models.

Gene and MicroRNA transcriptome analysis of Parkinson's related LRRK2 mouse models.

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent cause of genetic Parkinson's disease (PD). The biological function of LRRK2 and how mutations lead to disease remain poorly defined. It has been proposed that LRRK2 could function in gene transcription regulation; however,...

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Bibliographic Details
Main Authors: Véronique Dorval, Wim Mandemakers, Francis Jolivette, Laetitia Coudert, Rachid Mazroui, Bart De Strooper, Sébastien S Hébert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3888428?pdf=render

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http://europepmc.org/articles/PMC3888428?pdf=render

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