Identification of the chemokine CX3CL1 as a new regulator of malignant cell proliferation in epithelial ovarian cancer.

BACKGROUND:Little is known about the molecules that contribute to the growth of epithelial ovarian carcinomas (EOC), which remain the most lethal gynecological cancer in women. The chemokine Fractalkine/CX(3)CL1 has been widely reported to play a biologically relevant role in tumor growth and spread...

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Bibliographic Details
Main Authors: Françoise Gaudin, Salam Nasreddine, Anne-Claire Donnadieu, Dominique Emilie, Christophe Combadière, Sophie Prévot, Véronique Machelon, Karl Balabanian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3131275?pdf=render