Direct Renin Inhibitor is Better than Angiotensin II Receptor Blocker for Intrarenal Arterioles

Background/Aims: We have reported that the long-term administration of angiotensin II receptor blockers (ARBs) induced unusual proliferative changes of renal afferent arteriolar smooth muscle cells (SMCs) in rats, associated with the overproduction of renin. In this study, we examined that a direct...

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Bibliographic Details
Main Authors: Yohko Nagai, Kazushige Nakanishi, Nobuaki Yamanaka
Format: Article
Language:English
Published: Karger Publishers 2016-08-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:http://www.karger.com/Article/FullText/443459