Effects of Long-Term Endogenous Corticosteroid Exposure on Brain Volume and Glial Cells in the AdKO Mouse

Effects of Long-Term Endogenous Corticosteroid Exposure on Brain Volume and Glial Cells in the AdKO Mouse

Chronic exposure to high circulating levels of glucocorticoids has detrimental effects on health, including metabolic abnormalities, as exemplified in Cushing’s syndrome (CS). Magnetic resonance imaging (MRI) studies have found volumetric changes in gray and white matter of the brain in CS patients...

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Bibliographic Details
Main Authors: Jorge Miguel Amaya, Ernst Suidgeest, Isabelle Sahut-Barnola, Typhanie Dumontet, Nathanaëlle Montanier, Guilhem Pagès, Cécile Keller, Louise van der Weerd, Alberto M. Pereira, Antoine Martinez, Onno C. Meijer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neuroscience
Subjects:
glucocorticoid
glia
myelin basic protein
glial fibrillary acidic protein
ionized calcium binding adaptor molecule 1
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.604103/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.604103/full

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