A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

Antibiotic resistance is a major threat across the whole healthcare spectrum. Here, the authors report on the development of biodegradable guanidinium functionalized polycarbonates and demonstrate antimicrobial activity against drug resistant infections.

Bibliographic Details
Main Authors: Willy Chin, Guansheng Zhong, Qinqin Pu, Chuan Yang, Weiyang Lou, Paola Florez De Sessions, Balamurugan Periaswamy, Ashlynn Lee, Zhen Chang Liang, Xin Ding, Shujun Gao, Collins Wenhan Chu, Simone Bianco, Chang Bao, Yen Wah Tong, Weimin Fan, Min Wu, James L. Hedrick, Yi Yan Yang
Format: Article
Language:English
Published: Nature Publishing Group 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03325-6

Internet

https://doi.org/10.1038/s41467-018-03325-6

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