Molecular Docking and Preclinical Study of Five-Membered S,S-Palladaheterocycle as Hepatoprotective Agent

Molecular Docking and Preclinical Study of Five-Membered S,S-Palladaheterocycle as Hepatoprotective Agent

Purpose: In order to investigate mechanisms underlying the hepatoprotective action of S,Spalladaheterocycle, inhibition of cytochromes P450 has been modeled by molecular docking of four palladaheterocycle stereoisomers to the active sites of an enzymatic oxidase system. To obtain a deeper insight in...

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Bibliographic Details
Main Authors: Nail Salavatovich Akhmadiev, Albina Midkhatovna Galimova, Vnira Rakhimovna Akhmetova, Veronika Radievna Khairullina, Rozaliia Akramovna Galimova, Eduard Feliksovich Agletdinov, Askhat Gabdrahmanovich Ibragimov, Valery Alekseevich Kataev
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2019-10-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
cytochrome p450 cyp2e1
hepatoprotective activity
liver
molecular docking simulation
palladaheterocycle
preclinical study
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-27481

Internet

https://apb.tbzmed.ac.ir/PDF/apb-27481

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