Binding of Androgen- and Estrogen-Like Flavonoids to Their Cognate (Non)Nuclear Receptors: A Comparison by Computational Prediction

Binding of Androgen- and Estrogen-Like Flavonoids to Their Cognate (Non)Nuclear Receptors: A Comparison by Computational Prediction

Flavonoids are plant bioactives that are recognized as hormone-like polyphenols because of their similarity to the endogenous sex steroids 17β-estradiol and testosterone, and to their estrogen- and androgen-like activity. Most efforts to verify flavonoid binding to nuclear receptors (NRs) and explai...

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Bibliographic Details
Main Authors: Giulia D'Arrigo, Eleonora Gianquinto, Giulia Rossetti, Gabriele Cruciani, Stefano Lorenzetti, Francesca Spyrakis
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
molecular docking
androgens
estrogens
flavonoids
nuclear receptors
G protein-coupled receptors
Online Access:https://www.mdpi.com/1420-3049/26/6/1613

Internet

https://www.mdpi.com/1420-3049/26/6/1613

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