Biological evaluation of inhibitors of reverse transcriptase from HIV type-1

In the present work, Zn(II), Co(II) and Cr(II) metal complexes (3-5) of N-hydroxy-4-[(hydroxyimino)methyl]benzamidine ligand (2) were synthesized and their anti-HIV activity by inhibiting reverse transcriptase was explored. Structural characterization using NMR, FTIR, Mass, UV-Vis spectra, TGA, magn...

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Bibliographic Details
Main Authors: Hitendra Kumar Lautre, Taibi Ben Hadda, Snigdha Das, Ajai Kumar Pillai
Format: Article
Language:English
Published: Growing Science 2015-01-01
Series:Current Chemistry Letters
Subjects:
Online Access:http://www.growingscience.com/ccl/Vol4/ccl_2014_22.pdf