HIF1-alpha expression predicts survival of patients with squamous cell carcinoma of the oral cavity.

BACKGROUND: Oral squamous cell carcinoma is an important cause of death and morbidity wordwide and effective prognostic markers are still to be discovered. HIF1α protein is associated with hypoxia response and neovascularization, essential conditions for solid tumors survival. The relationship betwe...

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Bibliographic Details
Main Authors: Marcelo dos Santos, Ana Maria da Cunha Mercante, Iúri Drumond Louro, Antônio José Gonçalves, Marcos Brasilino de Carvalho, Eloiza Helena Tajara da Silva, Adriana Madeira Álvares da Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3445490?pdf=render