Volumetric muscle loss injury repair using in situ fibrin gel cast seeded with muscle-derived stem cells (MDSCs)

Volumetric muscle defect, caused by trauma or combat injuries, is a major health concern leading to severe morbidity. It is characterized by partial or full thickness loss of muscle and its bio-scaffold, resulting in extensive fibrosis and scar formation. Therefore, the ideal therapeutic option is t...

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Bibliographic Details
Main Authors: Nadine Matthias, Samuel D. Hunt, Jianbo Wu, Jonathan Lo, Laura A. Smith Callahan, Yong Li, Johnny Huard, Radbod Darabi
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S187350611830014X