Peripheral adaptive immunity of the triple transgenic mouse model of Alzheimer’s disease

Peripheral adaptive immunity of the triple transgenic mouse model of Alzheimer’s disease

Abstract Background Immunologic abnormalities have been described in peripheral blood and central nervous system of patients suffering from Alzheimer’s disease (AD), yet their role in the pathogenesis still remains poorly defined. Aim and methods We used the triple transgenic mouse model (3xTg-AD) t...

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Bibliographic Details
Main Authors: Isabelle St-Amour, Cristina R. Bosoi, Isabelle Paré, Prenitha Mercy Ignatius Arokia Doss, Manu Rangachari, Sébastien S. Hébert, Renée Bazin, Frédéric Calon
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Neuroinflammation
Subjects:
Adaptive immune system
Hematopoietic stem cell
Th17
Inflammation
Alzheimer’s disease
Neurodegenerative disease
Online Access:http://link.springer.com/article/10.1186/s12974-018-1380-5

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http://link.springer.com/article/10.1186/s12974-018-1380-5

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