NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction

NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction

The saw-scaled viper venom causes continued tissue damage that may cause death. Here the authors show that the venom attracts neutrophils to the bite site and induces neutrophil extracellular traps that capture venom components causing tissue damage, which can be prevented by enzymatic DNA degradati...

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Bibliographic Details
Main Authors: Gajanan D. Katkar, Mahalingam S. Sundaram, Somanathapura K. NaveenKumar, Basavarajaiah Swethakumar, Rachana D. Sharma, Manoj Paul, Gopalapura J. Vishalakshi, Sannaningaiah Devaraja, Kesturu S. Girish, Kempaiah Kemparaju
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11361

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https://doi.org/10.1038/ncomms11361

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