Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity.

Gram-positive bacteria assemble pili through class C sortase enzymes specialized in polymerizing pilin subunits into covalently linked, high-molecular-weight, elongated structures. Here we report the crystal structures of two class C sortases (SrtC1 and SrtC2) from Group B Streptococcus (GBS) Pilus...

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Bibliographic Details
Main Authors: Roberta Cozzi, Daniil Prigozhin, Roberto Rosini, Francesca Abate, Matthew J Bottomley, Guido Grandi, John L Telford, C Daniela Rinaudo, Domenico Maione, Tom Alber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3493515?pdf=render