A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin.

A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin.

Recently, we demonstrated that integrin adhesion to the extracellular matrix at the cleavage furrow is essential for cytokinesis of adherent cells. Here, we report that tight junction protein ZO-1 (Zonula Occludens-1) is required for successful cytokinesis in NCI-H460 cells plated on fibronectin. Th...

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Bibliographic Details
Main Authors: Saara Hämälistö, Jeroen Pouwels, Nicola de Franceschi, Markku Saari, Ylva Ivarsson, Pascale Zimmermann, Andreas Brech, Harald Stenmark, Johanna Ivaska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3742740?pdf=render

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http://europepmc.org/articles/PMC3742740?pdf=render

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