Coordinated hedgehog signaling induces new hair follicles in adult skin

Coordinated hedgehog signaling induces new hair follicles in adult skin

Hair follicle (HF) development is orchestrated by coordinated signals from adjacent epithelial and mesenchymal cells. In humans this process only occurs during embryogenesis and viable strategies to induce new HFs in adult skin are lacking. Here, we reveal that activation of Hedgehog (Hh) signaling...

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Bibliographic Details
Main Authors: Xiaoyan Sun, Alexandra Are, Karl Annusver, Unnikrishnan Sivan, Tina Jacob, Tim Dalessandri, Simon Joost, Anja Füllgrabe, Marco Gerling, Maria Kasper
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
hair follicle development
adult mouse skin
hedgehog signalling
mouse models
lineage tracing
Online Access:https://elifesciences.org/articles/46756

Internet

https://elifesciences.org/articles/46756

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