Stimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in mice.

Bone and lung metastases are responsible for the majority of deaths in patients with breast cancer. Following treatment of the primary cancer, emotional and psychosocial factors within this population precipitate time to recurrence and death, however the underlying mechanism(s) remain unclear. Using...

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Bibliographic Details
Main Authors: J Preston Campbell, Matthew R Karolak, Yun Ma, Daniel S Perrien, S Kathryn Masood-Campbell, Niki L Penner, Steve A Munoz, Andries Zijlstra, Xiangli Yang, Julie A Sterling, Florent Elefteriou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-07-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3398959?pdf=render