Troxerutin Protects Kidney Tissue against BDE-47-Induced Inflammatory Damage through CXCR4-TXNIP/NLRP3 Signaling

2,2′,4,4′-Tetrabromodiphenyl ether (BDE-47) induces oxidative stress in kidney cells, but the underlying mechanism remains poorly understood. Troxerutin, a natural flavonoid, has potential antioxidant and anti-inflammatory efficacy. In this study, we assessed the effect of troxerutin on kidney damag...

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Bibliographic Details
Main Authors: Qun Shan, Gui-hong Zheng, Xin-rui Han, Xin Wen, Shan Wang, Meng-qiu Li, Juan Zhuang, Zi-Feng Zhang, Bin Hu, Yanqiu Zhang, Yuan-Lin Zheng
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/9865495