Transcriptional profiling in <it>C. elegans </it>suggests DNA damage dependent apoptosis as an ancient function of the p53 family

<p>Abstract</p> <p>Background</p> <p>In contrast to the three mammalian p53 family members, p53, which is generally involved in DNA damage responses, and p63 and p73 which are primarily needed for developmental regulation, <it>cep-1 </it>encodes for the sing...

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Bibliographic Details
Main Authors: Rothblatt Jonathan, Grandien Kaj, Schumacher Björn, Greiss Sebastian, Gartner Anton
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/334