Genome-wide analysis of Müller glial differentiation reveals a requirement for Notch signaling in postmitotic cells to maintain the glial fate.

Previous studies have shown that Müller glia are closely related to retinal progenitors; these two cell types express many of the same genes and after damage to the retina, Müller glia can serve as a source for new neurons, particularly in non-mammalian vertebrates. We investigated the period of pos...

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Bibliographic Details
Main Authors: Branden R Nelson, Yumi Ueki, Sara Reardon, Mike O Karl, Sean Georgi, Byron H Hartman, Deepak A Lamba, Thomas A Reh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3149061?pdf=render