Antitumor Effect of MAb EMD 55900 Depends on EGF-R Expression and Histopathology

Antitumor Effect of MAb EMD 55900 Depends on EGF-R Expression and Histopathology

The proliferative stimulus of the epidermal growth factor (EGF) in human epithelial cells is mediated by its binding to the external domain of the EGF receptor (EGF-R). The purpose of this study was to investigate whether growth arrest of tumors treated with anti-EGFR MAb (EMD 55900) was dependent...

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Bibliographic Details
Main Authors: Christine Solbach, Anja Sterner-Kock, Marc Roller, Hans Georg Schnürch, Manfred Stegmuller, Gudrun Caspar-Bell, Petra Maria Schumm-Draeger, Manfred Kaufmann, Rainald Knecht
Format: Article
Language:English
Published: Elsevier 2002-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
EGFR
antibody
histology
EMD 55900
EMD 72000
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558602800173

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http://www.sciencedirect.com/science/article/pii/S1476558602800173

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